01-16.69 But what happens if the liver is already crammed full of fat?

QUOTE (emphasis mine): “INSULIN IS NORMALLY released when we eat. It directs some of the incoming glucose to be used as energy and some to be stored for later use. In the short term, glucose is stored as glycogen in the liver, but the liver’s storage space for glycogen is limited. Once it’s full, excess glucose is stored as fat: that is, the liver begins manufacturing fat from glucose through de novo lipogenesis. After the meal, as insulin levels fall, this process reverses. With no food energy coming in, stored food energy must be retrieved. Glycogen and fat stores in the liver are turned back into glucose and distributed to the rest of the body for energy.

The liver acts like a balloon. As energy comes in, it fills up. As energy is needed, it deflates. Balancing feeding and fasting periods over a day ensures that no net fat is gained or lost.

But what happens if the liver is already crammed full of fat? Insulin then tries to force more fat and sugar into the liver, even though it’s already full of fat and sugar. Just as it is more difficult to inflate a fully inflated balloon, insulin has more difficulty trying to shove more fat into a fatty liver. It takes higher and higher levels of insulin to move the same amount of food energy into a fatty liver. The body is now resistant to the efforts of insulin, since normal levels will not be enough to push sugar into the liver. Voilà—insulin resistance in the liver.

The liver, like an overinflated balloon, will try to expel the sugar back into circulation, so continuously high insulin levels are also required to keep it bottled up in the liver. If insulin levels start to drop, the stored fat and sugar comes whooshing out. To compensate, the body keeps raising its insulin levels. Thus, insulin resistance leads to higher insulin levels. High insulin levels encourage more storage of sugar and fat in the liver, which causes even more over-cramming of fat in the already fatty liver, causing more insulin resistance—a classic vicious cycle.” [1]

NOTE (my commentary)

What does this quote say?
What does it say that I should obey?
What is the wish? What are the outcomes?
What are the basic steps?
What are the obstacles?
Who needs to hear this?


SOURCE – Footnotes:
[1]  “The Obesity Code: Unlocking the Secrets of Weight Loss” by Dr. Jason Fung, Timothy Noakes

Please review the page How and Why We Use Quotes.
Key: Fung Origin: Last Revision: 01/09/2020

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