QUOTE from Dr Fung (emphasis mine):
“Experimentally, the constant infusion of insulin into a group of normal, healthy, non-diabetic volunteers can easily induce insulin resistance. Within days, insulin sensitivity drops by 20 to 40 percent. The implications are simply staggering. Healthy, young, lean men can be made insulin resistant simply by administering insulin – which causes insulin resistance. High doses of insulin used in T2DM can also induce insulin resistance.6 In one study patients were started on intensive insulin treatment in order to tightly control blood glucose. In six months, their average insulin dosage increased from zero to 100 units a day. Blood glucose control was indeed very good. But the more insulin they took, the more insulin resistance they got – a direct causal relationship, as inseparable as a shadow is from a body. Even as the blood glucose was improving, the T2DM was getting worse. Insulin creates insulin resistance. But insulin resistance also causes high insulin – a classic vicious, or self-reinforcing, cycle. Insulin drives up insulin resistance. This, in turn drives up insulin levels. The cycle keeps going around and around, one element reinforcing the other, until insulin is driven up to extremes.” [1]
NOTE (my commentary)
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Healthy, young, lean men can be made insulin resistant simply by administering insulin – which causes insulin resistance.
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But the more insulin they took, the more insulin resistance they got – a direct causal relationship
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STRATEGY:
DISCERNMENT QUESTIONS
What gets my attention?
Do I understand the need or problem?
Do I understand the potential solution?
Do I understand how to apply that strategy?
What questions do I have for the experts? What might be the answers?
Who needs to hear this?
What do I do next?
SOURCE – Footnotes:
[1] Chapter Three: What causes Type 2 diabetes? – Dr Jason Fung, in Diabetes Unpacked: Just Science and Sense. No Sugar Coating by Tim Noakes, Jason Fung, et. al. Kindle location 932.
Photo by Diabetes Care, Insulin, via Flickr
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Fung-10-31.35 Origin: Last Revision: 05/04/2021.